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Cannabinoids

Re-Medical Topical Patches are infused with broad-spectrum naturally derived cannabinoids.


Strains

There are two primary strains of Cannabis: Sativa and Indica. Today, there are many cultivar hybrids of both.
The different strains of cannabis contain different blends of cannabinoids. Many people report experiencing different medicinal effects from different strains. Indica dominant strains are higher in Cannabidiol (CBD), sativa dominant strains are higher in the THC cannabinoid.

Indica dominant strains are short dense plants, with broad leaves and often grow a darker green. Indicas originally come from the hash producing countries of the world like Afghanistan, Morocco, and Tibet. They are short dense plants, with broad leaves and often grow a darker green. After flowering starts they will be mature in 6 to 8 weeks. The buds will be thick and dense, with flavors and aromas ranging from pungent skunk to sweet and fruity. The smoke from an Indica is generally a body type effect, relaxing and laid back. Indica's higher CBD than THC equals a much heavier, sleepy type of high. Indica plants have a heavy, stony high that is relaxing and can help different medical problems. Results indicated that C. indica strains measured THC 19.6%, CBD <0.2% and CBN <0.5%.

Sativa dominant strains are tall, thin plants, with much narrower leaves and grow a lighter green in color. Hybrids will vary in their composition of THC, CBD and other cannabinoids, and are often referred to based upon the dominant cannabinoid ratio inherited from their lineage; indica, mostly indica, indica /sativa, mostly sativa, or pure sativa. Sativas are just about the opposite of indicas. They are tall, thin plants, with much narrower leaves and grow a lighter green in color. They grow very quickly and can reach heights of 20 feet in a single season. They originally come from Colombia, Mexico, Thailand and Southeast Asia. Once flowering has begun, they can take anywhere from 10 to 16 weeks to fully mature. Flavors range from earthy to sweet and fruity. The effects of a Sativa is cerebral, up and energetic. Results from a drug detection laboratory indicated that C. sativa measured: THC 23.7%, CBD <0.1% and CBN <0.1%.


Cannabinoids

A range of differentiable effects has been ascribed to THC (tetrahydrocannabinol is the primary psychoactive component of marijuana) and CBD (cannabidiol, a non-psychoactive molecule related to THC) when administered in purified form.

Delta-9-Tetrahydrocannabinol (THC)
A psychoactive cannabinoid responsible for many of the effects experienced by the cannabis user. Mild to moderate pain relief, relaxation, insomnia and appetite stimulation. THC has been demonstrated to have anti-depressant effects. The majority of strains range from 12-21% THC with very potent and carefully prepared strains reaching even higher. Average THC potency is about 16-17% in Northern CA. Recent research that suggests patients with a pre-disposition to schizophrenia and anxiety disorders should avoid high-THC cannabis.

Cannabidiol (CBD)
Occurs in many strains, at low levels, <1%. In rare cases, CBD can be the dominant cannabinoid, as high as 15% by weight. Popular CBD-rich strains (>4% CBD) include Sour Tsunami, Harlequin and Cannatonic. It can provide relief for chronic pain due to muscle spasticity, convulsions and inflammation. Offering relief for patients with MS, Fibromyalgia and Epilepsy. Some researchers feel it provides effective relief from anxiety-related disorders. CBD has also been shown to inhibit cancer cell growth when injected into breast and brain tumors in combination with THC.

Cannabinol (CBN)
An oxidative degradation product of THC. It may result from improper storage or curing and extensive processing, such as when making concentrates. It is usually formed when THC is exposed to UV light and oxygen over time. CBN has some psychoactive properties, about 10% of the strength of THC. CBN is thought by researchers to enhance the dizziness and disorientation users of cannabis may experience. It may cause feelings of grogginess and has been shown to reduce heart rate.

Cannabichromene (CBC)
A rare, non-psychoactive cannabinoid, usually found at low levels (<1%) when present. Research conducted has shown CBC has anti-depressant effects, 10x those of CBD. CBC has also been shown to improve the pain-relieving effects of THC. Studies have demonstrated that CBC has sedative effects, promoting relaxation.

Cannabigerol (CBG)
A non-psychoactive cannabinoid. It is commonly found in cannabis. CBG-acid is the precursor to both THC-acid and CBD-acid in the plant usually found at low levels (<1%) when present. Researchers have demonstrated both pain relieving and inflammation reducing effects. CBG reduces intraocular pressure, associated with glaucoma. CBG has been shown to have antibiotic properties and to inhibit platelet aggregation, which slows the rate of blood clotting.


Effects

Cannabinoid receptors (CB1 and CB2) exist throughout the human body: immune system, brain, spine, gastrointestinal system, peripheral nervous system, to only name a few.

Psychological effects of THC can include relaxation, euphoria, altering perception of time, color and space, short term memory loss, lack of inhibition, dizziness, changes in appetite, and in some cases sudden changes in mood including increased irritability. For some individuals, symptoms of schizophrenia may be worsened.

Undesired physical effects, mostly from smoking cannabis, often include dry mouth, dry and bloodshot eyes, and increased heart rate.

Effects usually last 2 to 3 hours after smoking, and there is no clear evidence of lasting effects.

Ability to drive and operate machinery are impaired due to effects on motor skills and depth perception. Patients are advised not to do any activity which involves judgment or coordination.

Many research studies and national health systems have recognized numerous positive effects of cannabinoids. Some of these include:

Pain, Peripheral neuropathy, Cancer pain, Post-amputation Pain
Eating disorders, Anorexia, Wasting Syndrome
Alzheimer's Disease, Brain injury/stroke, Spinal cord injury
Nausea, Motion Sickness
Rheumatoid arthritis
HIV/AIDS
Cachexia
Cancer
Crohn's Disease
Bladder dysfunction
Epilepsy
Glaucoma
Migraine
Menstrual Cramps
Asthma
Depress./mental ill.
Fibromyalgia
Hypertension
Nail Patella Syndrome
Tourette's syndrome


Quotes

"There are a number of devastating disorders and symptoms for which marijuana has been used for centuries.
Marijuana is effective at relieving nausea and vomiting, spasticity, appetite loss, certain types of pain, and other debilitating symptoms. And it is extraordinarily safe -- safer than most medicines prescribed every day."

Lester Grinspoon, MD, Emeritus Professor of Psychiatry at Harvard Medical School, wrote in a Mar. 1, 2007 editorial in the Boston Globe titled "Marijuana as Wonder Drug"

"Research to date suggests that research into the medicinal uses of cannabis and cannabinoids has the potential to make exciting breakthroughs in the management of severe symptoms such as pain, spasm, bladder dysfunction and nausea and could therefore bring a dramatic improvement in quality of life."
UK's Medicinal Cannabis Research Foundation published on its website in Nov. 2001


History

"The use of cannabis for purposes of healing predates recorded history. The earliest written reference is found in the 15th century BC Chinese Pharmacopeia, the Rh-Ya."
National Institute on Drug Abuse (NIDA)

Click here for a comprehensive historical timeline


Cannabis Legalization Resources

http://www.cnn.com/2013/08/07/health/charlotte-child-medical-marijuana/
http://norml.org/
http://www.huffingtonpost.com/tag/pot-legalization
http://www.drugpolicy.org/marijuana-legalization-and-regulation
https://obamawhitehouse.archives.gov/ondcp/state-laws-related-to-marijuana
http://medicalmarijuana.procon.org/view.resource.php?resourceID=002481
http://www.marijuanacontrollegalizationrevenueact.com/
http://www.governing.com/gov-data/state-marijuana-laws-map-medical-recreational.html
 

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Re-Medical, Inc. provides a topical patch that uses some aspects related to the regulated cannabis industry. Re-Medical, Inc. does not grow, harvest, distribute or sell cannabis or any substances that violate United States law or the Controlled Substances Act, nor do they intend to do so in the future. As of March 21, 2014, twenty states and the District of Columbia allow its citizens to use Medical Marijuana and voters in the states of Colorado and Washington approved ballot measures to legalize cannabis for adult use. The state laws are in conflict with the federal Controlled Substances Act. The current administration has effectively stated that it is not an efficient use of resources to direct federal law enforcement agencies to prosecute those lawfully abiding by state designated laws allowing the use and distribution of medical marijuana. However, there is no guarantee that the current administration, nor any future administration, will not change this policy and decide to enforce the federal laws strongly. Any such change in the federal government’s enforcement of current federal laws could cause significant financial changes to the Company. While we do not intend to harvest, distribute or sell cannabis or cannabis related products, we may be harmed by a change in enforcement by federal or state governments.